![]() It is wise to see the results as per guidelines established by the lab running your sample. What Do The Test Results Mean?īecause the normal and abnormal reference range for the Sm And Sm/RNP Antibodies Test depends upon your laboratory and their testing method. In rare cases, people might feel a bit dizzy, lightheaded, or even faint, but the symptoms do not last long. Are There Any Risks To This Test?Īn Sm and Sm/RNP Antibodies Test is one of the harmless, most common tests required for confirming the actual diagnosis. In that case, you might need to fast for at least 8-10 hours and even stop using your routine medication, supplements, and vitamins to avoid misinterpretation of the results. Suppose your doctor recommends other tests along with this test. Since Sm And Sm/RNP Antibodies Test is a standard blood test, you don't have to do anything special before the procedure. ![]() Once the sample is collected, it is sent to the laboratory for further analysis. They will then insert the needle to collect an adequate blood sample as per your doctor's recommendation. During the procedure, the lab technician first cleans your arm with an antiseptic and then ties an elastic band around it to make the veins visible. What Kind Of Sample Is Required For The Test?įor Sm And Sm/RNP Antibodies Test, a doctor, healthcare provider, or lab technician will draw a blood sample, usually from a vein in your arm. Butterfly skin rash on cheeks and bridge of the noseĮarly indications and signs/symptoms of mixed connective tissue disease include the following:.Symptoms of systemic lupus erythematosus include: Your doctor or health care provider will ask you to undergo the Sm And Sm/RNP Antibodies Test if you show symptoms of SLE, mixed connective tissue disease, rheumatoid arthritis, and scleroderma. Why And When Do You Need A Sm And Sm/RNP Antibodies Test? Depending on your health condition, age, and severity of symptoms, some other tests will also become mandatory in identifying the type of disorder you might be affected by. Your doctor or care provider will recommend this test as a follow-up test for positive antinuclear antibody or ANA test results. Elevated levels of RNP antibodies are often seen in people with connective tissue disorders such as lupus, scleroderma, and rheumatoid arthritis. Testing for different antibodies at once can help differentiate these antibodies and their characteristics. Usually, autoimmune conditions are very hard to diagnose as they display similar symptoms to one another. In such circumstances, the antibodies are produced by the immune system and attack the body's healthy cells and tissues. RNP is a kind of antibody that is abundantly found in people with autoimmune disorders or autoimmune conditions. What Is The Test Used For?ĭoctors or healthcare professionals use the Sm And Sm/RNP Antibodies Test to measure the level of anti-ribonucleoprotein or RNP antibodies in your blood serum. High-tittered RNP antibodies are associated with overlap syndrome and MCTD. The antibodies to Sm are known as a specific serologic marker due to the presence with multiple rheumatic disorders like SLE, scleroderma, and even rheumatoid arthritis. The Sm antigen was acknowledged during 1966 as a saline, soluble, non-histone glycoprotein independent of the DNA or RNA for the antigenicity qualities. Therefore, at times, you might need to undergo another secondary confirmatory testing to detect antibodies to ENA. On the contrary, some antibodies to ENA do not indicate a positive ANA test as well. ![]() The ANA test has been used as a screening method for such antibodies however, it cannot indicate or specify the presence of any particular antibody. These antibodies are also helpful for your doctor during the differential diagnosis related to other chronic, systemic, autoimmune rheumatic disorders such as systemic sclerosis, Sjogren syndrome, dermatomyositis, polymyositis, and other similar overlap syndromes. It serves as a reliable and efficient way of confirming diagnosis related to SLE, i.e., systemic lupus erythematosus and MCTD, i.e., mixed connective tissue disease using a positive ANA result. This test is used to measure Sm and Sm/RNP antibodies in your bloodstream. Also Known As: Anti-Ribonucleic Protein Antigen, Anti-ENA Antibody, ENA Antibodies, Ribonuclear Protein Antibody, Anti-Smith Antibody, RNP Antibody What Is A Sm And Sm/RNP Antibodies Test?
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